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Targeting BRAF for patients with melanoma
The prognosis of patients with metastatic melanoma is poor and not influenced by systemic therapy with cytotoxic drugs. New targeted agents directed against the RAS-RAF-MEK-ERK pathway show promising activity in early clinical development and particular interest is focused on selective inhibitors of...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049553/ https://www.ncbi.nlm.nih.gov/pubmed/21139585 http://dx.doi.org/10.1038/sj.bjc.6606030 |