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Comparison of methods for handling missing data on immunohistochemical markers in survival analysis of breast cancer
BACKGROUND: Tissue micro-arrays (TMAs) are increasingly used to generate data of the molecular phenotype of tumours in clinical epidemiology studies, such as studies of disease prognosis. However, TMA data are particularly prone to missingness. A variety of methods to deal with missing data are avai...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049587/ https://www.ncbi.nlm.nih.gov/pubmed/21266980 http://dx.doi.org/10.1038/sj.bjc.6606078 |