No association between germline allele-specific expression of TGFBR1 and colorectal cancer risk in Caucasian and Ashkenazi populations

BACKGROUND: Germline allele-specific expression (ASE) of the TGFBR1 gene has been reported as a strong risk factor for colorectal cancer (CRC) with an odds ratio close to 9. Considering the potential implications of the finding, we undertook the task of validating the initial results in this study....

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Detalles Bibliográficos
Autores principales: Seguí, N, Stevens, K N, Guinó, E, Rozek, L S, Moreno, V R, Capellá, G, Gruber, S B, Valle, L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049588/
https://www.ncbi.nlm.nih.gov/pubmed/21224855
http://dx.doi.org/10.1038/sj.bjc.6606079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049588/
https://www.ncbi.nlm.nih.gov/pubmed/21224855
http://dx.doi.org/10.1038/sj.bjc.6606079

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