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No association between germline allele-specific expression of TGFBR1 and colorectal cancer risk in Caucasian and Ashkenazi populations
BACKGROUND: Germline allele-specific expression (ASE) of the TGFBR1 gene has been reported as a strong risk factor for colorectal cancer (CRC) with an odds ratio close to 9. Considering the potential implications of the finding, we undertook the task of validating the initial results in this study....
Autores principales: | Seguí, N, Stevens, K N, Guinó, E, Rozek, L S, Moreno, V R, Capellá, G, Gruber, S B, Valle, L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049588/ https://www.ncbi.nlm.nih.gov/pubmed/21224855 http://dx.doi.org/10.1038/sj.bjc.6606079 |
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