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CXC receptor-4 mRNA silencing abrogates CXCL12-induced migration of colorectal cancer cells
BACKGROUND: Interactions between CXCR4 and its ligand CXCL12 have been shown to be involved in cancer progression in colorectal cancer (CRC). We performed a comparative CXCL12/CXCR4 expression analysis and assessed the effect of external CXCL12 stimulation on migration of CRC cells without and with...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049756/ https://www.ncbi.nlm.nih.gov/pubmed/21349176 http://dx.doi.org/10.1186/1479-5876-9-22 |