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CXC receptor-4 mRNA silencing abrogates CXCL12-induced migration of colorectal cancer cells

BACKGROUND: Interactions between CXCR4 and its ligand CXCL12 have been shown to be involved in cancer progression in colorectal cancer (CRC). We performed a comparative CXCL12/CXCR4 expression analysis and assessed the effect of external CXCL12 stimulation on migration of CRC cells without and with...

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Detalles Bibliográficos
Autores principales:	Rubie, Claudia, Frick , Vilma O, Ghadjar, Pirus, Wagner, Mathias, Justinger, Christoph, Faust, Sabrina K, Vicinus, Benjamin, Gräber, Stefan, Kollmar, Otto, Schilling, Martin K
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049756/ https://www.ncbi.nlm.nih.gov/pubmed/21349176 http://dx.doi.org/10.1186/1479-5876-9-22

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