Blood-Brain Barrier Impairment in an Animal Model of MPS III B

BACKGROUND: Sanfilippo syndrome type B (MPS III B) is caused by a deficiency of α-N-acetylglucosaminidase enzyme, leading to accumulation of heparan sulfate within lysosomes and eventual progressive cerebral and systemic multiple organ abnormalities. However, little is known about the competence of...

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Detalles Bibliográficos
Autores principales: Garbuzova-Davis, Svitlana, Louis, Michael K., Haller, Edward M., Derasari, Hiranya M., Rawls, Ashley E., Sanberg, Paul R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049764/
https://www.ncbi.nlm.nih.gov/pubmed/21408219
http://dx.doi.org/10.1371/journal.pone.0016601

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049764/
https://www.ncbi.nlm.nih.gov/pubmed/21408219
http://dx.doi.org/10.1371/journal.pone.0016601

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