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Blood-Brain Barrier Impairment in an Animal Model of MPS III B

BACKGROUND: Sanfilippo syndrome type B (MPS III B) is caused by a deficiency of α-N-acetylglucosaminidase enzyme, leading to accumulation of heparan sulfate within lysosomes and eventual progressive cerebral and systemic multiple organ abnormalities. However, little is known about the competence of...

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Detalles Bibliográficos
Autores principales:	Garbuzova-Davis, Svitlana, Louis, Michael K., Haller, Edward M., Derasari, Hiranya M., Rawls, Ashley E., Sanberg, Paul R.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049764/ https://www.ncbi.nlm.nih.gov/pubmed/21408219 http://dx.doi.org/10.1371/journal.pone.0016601

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