Cargando…
Optineurin Is Required for CYLD-Dependent Inhibition of TNFα-Induced NF-κB Activation
The nuclear factor kappa B (NF-κB) regulates genes that function in diverse cellular processes like inflammation, immunity and cell survival. The activation of NF-κB is tightly controlled and the deubiquitinase CYLD has emerged as a key negative regulator of NF-κB signalling. Optineurin, mutated in...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049778/ https://www.ncbi.nlm.nih.gov/pubmed/21408173 http://dx.doi.org/10.1371/journal.pone.0017477 |