Early T Cell Signalling Is Reversibly Altered in PD-1(+) T Lymphocytes Infiltrating Human Tumors

To improve cancer immunotherapy, a better understanding of the weak efficiency of tumor-infiltrating T lymphocytes (TIL) is necessary. We have analyzed the functional state of human TIL immediately after resection of three types of tumors (NSCLC, melanoma and RCC). Several signalling pathways (calci...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Shu-Fang, Fouquet, Stéphane, Chapon, Maxime, Salmon, Hélène, Regnier, Fabienne, Labroquère, Karine, Badoual, Cécile, Damotte, Diane, Validire, Pierre, Maubec, Eve, Delongchamps, Nicolas B., Cazes, Aurélie, Gibault, Laure, Garcette, Marylène, Dieu-Nosjean, Marie-Caroline, Zerbib, Marc, Avril, Marie-Françoise, Prévost-Blondel, Armelle, Randriamampita, Clotilde, Trautmann, Alain, Bercovici, Nadège
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049782/
https://www.ncbi.nlm.nih.gov/pubmed/21408177
http://dx.doi.org/10.1371/journal.pone.0017621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049782/
https://www.ncbi.nlm.nih.gov/pubmed/21408177
http://dx.doi.org/10.1371/journal.pone.0017621

Ejemplares similares