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Genomic and Proteomic Analysis of the Impact of Mitotic Quiescence on the Engraftment of Human CD34(+) Cells

It is well established that in adults, long-term repopulating hematopoietic stem cells (HSC) are mitotically quiescent cells that reside in specialized bone marrow (BM) niches that maintain the dormancy of HSC. Our laboratory demonstrated that the engraftment potential of human HSC (CD34(+) cells) f...

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Detalles Bibliográficos
Autores principales: Chitteti, Brahmananda Reddy, Liu, Yunlong, Srour, Edward F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049784/
https://www.ncbi.nlm.nih.gov/pubmed/21408179
http://dx.doi.org/10.1371/journal.pone.0017498