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Selective killing of Burkitt's lymphoma cells by mBAFF-targeted delivery of PinX1

Increased expression of BAFF (B cell-activating factor belonging to the TNF family) and its receptors has been identified in numerous B-cell malignancies. A soluble human BAFF mutant (mBAFF), binding to BAFF receptors but failing to activate B-lymphocyte proliferation, may function as a competitive...

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Detalles Bibliográficos
Autores principales: Zhang, L, Jiang, Y, Zheng, Y, Zeng, Y, Yang, Z, Huang, G, Liu, D, Gao, M, Shen, X, Wu, G, Yan, X, He, F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049869/
https://www.ncbi.nlm.nih.gov/pubmed/21102426
http://dx.doi.org/10.1038/leu.2010.261