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Selective killing of Burkitt's lymphoma cells by mBAFF-targeted delivery of PinX1
Increased expression of BAFF (B cell-activating factor belonging to the TNF family) and its receptors has been identified in numerous B-cell malignancies. A soluble human BAFF mutant (mBAFF), binding to BAFF receptors but failing to activate B-lymphocyte proliferation, may function as a competitive...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049869/ https://www.ncbi.nlm.nih.gov/pubmed/21102426 http://dx.doi.org/10.1038/leu.2010.261 |