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The effects of midazolam and sevoflurane on the GABA(A) receptors with alternatively spliced variants of the γ2 subunit

BACKGROUND: Emergence agitation after sevoflurane anesthesia in children can be prevented by midazolam. Alternative splicing of the GABA(A) receptor changes with age. Therefore, we hypothesized that alternative splicing of the γ2 subunit affects the GABA current when applying sevoflurane and midazol...

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Detalles Bibliográficos
Autores principales: Eom, Woosik, Lee, Jung Min, Park, Jeongmi, Choi, Kyungho, Jung, Sung-Jun, Kim, Hee-Soo
Formato: Texto
Lenguaje:English
Publicado: The Korean Society of Anesthesiologists 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049878/
https://www.ncbi.nlm.nih.gov/pubmed/21390166
http://dx.doi.org/10.4097/kjae.2011.60.2.109