Obesity impairs skeletal muscle AMPK signaling during exercise: role of AMPKα2 in the regulation of exercise capacity in vivo

OBJECTIVE: Skeletal muscle AMP-activated protein kinase (AMPK)α2 activity is impaired in obese, insulin resistant individuals during exercise. We determined whether this defect contributes to the metabolic dysregulation and reduced exercise capacity observed in the obese state. DESIGN: C57BL/6J wild...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee-Young, Robert S., Ayala, Julio E., Fueger, Patrick T., Mayes, Wesley H., Kang, Li, Wasserman, David H.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049903/
https://www.ncbi.nlm.nih.gov/pubmed/21079619
http://dx.doi.org/10.1038/ijo.2010.220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3049903/
https://www.ncbi.nlm.nih.gov/pubmed/21079619
http://dx.doi.org/10.1038/ijo.2010.220

Ejemplares similares