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mTOR inhibition reduces cellular proliferation and sensitizes pituitary adenoma cells to ionizing radiation

BACKGROUND: Pituitary adenomas are the most frequent brain tumor in adults. Although histologically benign, pituitary tumors cause significant morbidity and mortality. Neurosurgery and medical therapeutics may lessen the morbidity and mortality associated with pituitary tumors; however, these treatm...

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Detalles Bibliográficos
Autores principales: Sukumari-Ramesh, Sangeetha, Singh, Nagendra, Dhandapani, Krishnan M., Vender, John R.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050059/
https://www.ncbi.nlm.nih.gov/pubmed/21427787
http://dx.doi.org/10.4103/2152-7806.77029