DNMT1 Maintains Progenitor Function in Self-Renewing Somatic Tissue

Progenitor cells maintain self-renewing tissues throughout life by sustaining their capacity for proliferation while suppressing cell cycle exit and terminal differentiation1,2. DNA methylation3,4,5 provides a potential epigenetic mechanism for the cellular memory needed to preserve the somatic prog...

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Detalles Bibliográficos
Autores principales: Sen, George L., Reuter, Jason A., Webster, Daniel E., Zhu, Lilly, Khavari, Paul A.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050546/
https://www.ncbi.nlm.nih.gov/pubmed/20081831
http://dx.doi.org/10.1038/nature08683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050546/
https://www.ncbi.nlm.nih.gov/pubmed/20081831
http://dx.doi.org/10.1038/nature08683

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