Enantioselective syntheses of carbocyclic nucleosides 5′-homocarbovir, epi-4′-homocarbovir, and their cyclopropylamine analogs using facially selective Pd-mediated allylations

Carbocyclic nucleosides (−)-5′-homocarbovir and (+)-epi-4′-homocarbovir were prepared from an acylnitroso-derived hetero Diels–Alder cycloadduct. A kinetic enzymatic resolution generated an enantiopure aminocyclopentenol and Pd(0)-mediated decarboxylative allylations of allyl 2,2,2-trifluoroethyl ma...

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Detalles Bibliográficos
Autores principales: Tardibono, Lawrence P., Miller, Marvin J., Balzarini, Jan
Formato: Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050557/
https://www.ncbi.nlm.nih.gov/pubmed/21399715
http://dx.doi.org/10.1016/j.tet.2010.11.097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050557/
https://www.ncbi.nlm.nih.gov/pubmed/21399715
http://dx.doi.org/10.1016/j.tet.2010.11.097

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