Cargando…

Calcineurin and ATF3: opposite roles in squamous skin cancer

Calcineurin inhibitors such as cyclosporin A (CsA) are the mainstay of immunosuppressive treatment for organ transplant recipients. Squamous cell carcinoma (SCC) of the skin is a major complication of treatment with these drugs, with a 65–100 fold higher risk than in the normal population1. By contr...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Xunwei, Nguyen, Bach-Cuc, Dziunycz, Piotr, Chang, Sungeun, Brooks, Yang, Lefort, Karine, Hofbauer, Günther F.L., Dotto, G. Paolo
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050632/
https://www.ncbi.nlm.nih.gov/pubmed/20485437
http://dx.doi.org/10.1038/nature08996