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Calcineurin and ATF3: opposite roles in squamous skin cancer
Calcineurin inhibitors such as cyclosporin A (CsA) are the mainstay of immunosuppressive treatment for organ transplant recipients. Squamous cell carcinoma (SCC) of the skin is a major complication of treatment with these drugs, with a 65–100 fold higher risk than in the normal population1. By contr...
Autores principales: | Wu, Xunwei, Nguyen, Bach-Cuc, Dziunycz, Piotr, Chang, Sungeun, Brooks, Yang, Lefort, Karine, Hofbauer, Günther F.L., Dotto, G. Paolo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050632/ https://www.ncbi.nlm.nih.gov/pubmed/20485437 http://dx.doi.org/10.1038/nature08996 |
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