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High cell density cultivation of Escherichia coli K4 in a microfiltration bioreactor: a step towards improvement of chondroitin precursor production

BACKGROUND: The bacteria Escherichia coli K4 produces a capsular polysaccharide (K4 CPS) whose backbone is similar to the non sulphated chondroitin chain. The chondroitin sulphate is one of the major components of the extra-cellular matrix of the vertebrate connective tissues and a high value molecu...

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Detalles Bibliográficos
Autores principales: Restaino, Odile Francesca, Cimini, Donatella, De Rosa, Mario, Catapano, Angela, Schiraldi, Chiara
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050683/
https://www.ncbi.nlm.nih.gov/pubmed/21324163
http://dx.doi.org/10.1186/1475-2859-10-10