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Effects of polymorphisms in ovine and caprine prion protein alleles on cell-free conversion

In sheep polymorphisms of the prion gene (PRNP) at the codons 136, 154 and 171 strongly influence the susceptibility to scrapie and bovine spongiform encephalopathy (BSE) infections. In goats a number of other gene polymorphisms were found which are suspected to trigger similar effects. However, no...

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Detalles Bibliográficos
Autores principales: Eiden, Martin, Soto, Elizabeth Ortega, Mettenleiter, Thomas C, Groschup, Martin H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050705/
https://www.ncbi.nlm.nih.gov/pubmed/21324112
http://dx.doi.org/10.1186/1297-9716-42-30