A simple work flow for biologically inspired model reduction - application to early JAK-STAT signaling

BACKGROUND: Modeling of biological pathways is a key issue in systems biology. When constructing a model, it is tempting to incorporate all known interactions of pathway species, which results in models with a large number of unknown parameters. Fortunately, unknown parameters need not necessarily b...

Descripción completa

Detalles Bibliográficos
Autores principales: Quaiser, Tom, Dittrich, Anna, Schaper, Fred, Mönnigmann, Martin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050741/
https://www.ncbi.nlm.nih.gov/pubmed/21338487
http://dx.doi.org/10.1186/1752-0509-5-30

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050741/
https://www.ncbi.nlm.nih.gov/pubmed/21338487
http://dx.doi.org/10.1186/1752-0509-5-30

Ejemplares similares