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A simple work flow for biologically inspired model reduction - application to early JAK-STAT signaling
BACKGROUND: Modeling of biological pathways is a key issue in systems biology. When constructing a model, it is tempting to incorporate all known interactions of pathway species, which results in models with a large number of unknown parameters. Fortunately, unknown parameters need not necessarily b...
Autores principales: | Quaiser, Tom, Dittrich, Anna, Schaper, Fred, Mönnigmann, Martin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050741/ https://www.ncbi.nlm.nih.gov/pubmed/21338487 http://dx.doi.org/10.1186/1752-0509-5-30 |
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