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Hippocampal expression of murine TNFα results in attenuation of amyloid deposition in vivo

Fibrillar amyloid β (fAβ) peptide is the major component of Aβ plaques in the brains of Alzheimer's disease (AD) patients. Inflammatory mediators have previously been proposed to be drivers of Aβ pathology in AD patients by increasing amyloidogenic processing of APP and promoting Aβ accumulatio...

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Detalles Bibliográficos
Autores principales: Chakrabarty, Paramita, Herring, Amanda, Ceballos-Diaz, Carolina, Das, Pritam, Golde, Todd E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050766/
https://www.ncbi.nlm.nih.gov/pubmed/21324189
http://dx.doi.org/10.1186/1750-1326-6-16