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Quantitative Interpretation of a Genetic Model of Carcinogenesis Using Computer Simulations
The genetic model of tumorigenesis by Vogelstein et al. (V theory) and the molecular definition of cancer hallmarks by Hanahan and Weinberg (W theory) represent two of the most comprehensive and systemic understandings of cancer. Here, we develop a mathematical model that quantitatively interprets t...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050823/ https://www.ncbi.nlm.nih.gov/pubmed/21408146 http://dx.doi.org/10.1371/journal.pone.0016859 |