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Acellular Pertussis Booster in Adolescents Induces Th1 and Memory CD8(+) T Cell Immune Response

In a number of countries, whole cell pertussis vaccines (wcP) were replaced by acellular vaccines (aP) due to an improved reactogenicity profile. Pertussis immunization leads to specific antibody production with the help of CD4(+) T cells. In earlier studies in infants and young children, wcP vaccin...

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Detalles Bibliográficos
Autores principales: Rieber, Nikolaus, Graf, Anna, Hartl, Dominik, Urschel, Simon, Belohradsky, Bernd H., Liese, Johannes
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050840/
https://www.ncbi.nlm.nih.gov/pubmed/21408149
http://dx.doi.org/10.1371/journal.pone.0017271