Soluble Frizzled-7 receptor inhibits Wnt signaling and sensitizes hepatocellular carcinoma cells towards doxorubicin

BACKGROUND: There are limited therapeutic options for hepatocellular carcinoma (HCC), the most common liver malignancy worldwide. Recent studies have identified the Frizzled-7 receptor (FZD7), important for activation of Wnt-mediated signaling, as a potential therapeutic target for HCC and other can...

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Detalles Bibliográficos
Autores principales: Wei, Wei, Chua, Mei-Sze, Grepper, Susan, So, Samuel K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050858/
https://www.ncbi.nlm.nih.gov/pubmed/21314951
http://dx.doi.org/10.1186/1476-4598-10-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050858/
https://www.ncbi.nlm.nih.gov/pubmed/21314951
http://dx.doi.org/10.1186/1476-4598-10-16

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