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Soluble Frizzled-7 receptor inhibits Wnt signaling and sensitizes hepatocellular carcinoma cells towards doxorubicin

BACKGROUND: There are limited therapeutic options for hepatocellular carcinoma (HCC), the most common liver malignancy worldwide. Recent studies have identified the Frizzled-7 receptor (FZD7), important for activation of Wnt-mediated signaling, as a potential therapeutic target for HCC and other can...

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Detalles Bibliográficos
Autores principales:	Wei, Wei, Chua, Mei-Sze, Grepper, Susan, So, Samuel K
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050858/ https://www.ncbi.nlm.nih.gov/pubmed/21314951 http://dx.doi.org/10.1186/1476-4598-10-16

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