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Sodium ion channel mutations in glioblastoma patients correlate with shorter survival

BACKGROUND: Glioblastoma Multiforme (GBM) is the most common and invasive astrocytic tumor associated with dismal prognosis. Treatment for GBM patients has advanced, but the median survival remains a meager 15 months. In a recent study, 20,000 genes from 21 GBM patients were sequenced that identifie...

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Detalles Bibliográficos
Autores principales: Joshi, Avadhut D, Parsons, D Williams, Velculescu, Victor E, Riggins, Gregory J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050859/
https://www.ncbi.nlm.nih.gov/pubmed/21314958
http://dx.doi.org/10.1186/1476-4598-10-17