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A Role for Amyloid in Cell Aggregation and Biofilm Formation

Cell adhesion molecules in Saccharomyces cerevisiae and Candida albicans contain amyloid-forming sequences that are highly conserved. We have now used site-specific mutagenesis and specific peptide perturbants to explore amyloid-dependent activity in the Candida albicans adhesin Als5p. A V326N subst...

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Detalles Bibliográficos
Autores principales: Garcia, Melissa C., Lee, Janis T., Ramsook, Caleen B., Alsteens, David, Dufrêne, Yves F., Lipke, Peter N.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050909/
https://www.ncbi.nlm.nih.gov/pubmed/21408122
http://dx.doi.org/10.1371/journal.pone.0017632