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Dipyridamole with Low-Dose Aspirin Augments the Infarct Size-Limiting Effects of Simvastatin

PURPOSE: Statins protect against ischemia-reperfusion injury and limit myocardial infarct size (IS). This effect is dependent on increased generation of adenosine by ecto-5′ nucleotidase and downstream activation of cyclooxygenase-2 (COX2). Dipyridamole (DIP) augments the IS-limiting effects of stat...

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Detalles Bibliográficos
Autores principales: Ye, Yumei, Long, Bo, Qian, Jinqiao, Perez-Polo, Jose R., Birnbaum, Yochai
Formato: Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051102/
https://www.ncbi.nlm.nih.gov/pubmed/20640495
http://dx.doi.org/10.1007/s10557-010-6252-x