A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells

Dendritic cells (DC) serve a key function in host defense, linking innate detection of microbes to the activation of pathogen-specific adaptive immune responses(1,2). Whether there is cell-intrinsic recognition of HIV-1 by host innate pattern-recognition receptors and subsequent coupling to antivira...

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Detalles Bibliográficos
Autores principales: Manel, Nicolas, Hogstad, Brandon, Wang, Yaming, Levy, David E., Unutmaz, Derya, Littman, Dan R.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051279/
https://www.ncbi.nlm.nih.gov/pubmed/20829794
http://dx.doi.org/10.1038/nature09337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051279/
https://www.ncbi.nlm.nih.gov/pubmed/20829794
http://dx.doi.org/10.1038/nature09337

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