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PLZF(+) T cells regulate memory-like CD8(+) T cell development

Several gene deficiency models promote the development of “innate CD8(+) T cells” that have diverse TCRs, but display a memory phenotype and rapidly produce cytokines. We here demonstrate that similar cells develop in Kruppel-Like Factor 2 (KLF2) deficient mice. However, this is not due to intrinsic...

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Detalles Bibliográficos
Autores principales: Weinreich, Michael A., Odumade, Oludare A., Jameson, Stephen C., Hogquist, Kristin A.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051359/
https://www.ncbi.nlm.nih.gov/pubmed/20601952
http://dx.doi.org/10.1038/ni.1898