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PLZF(+) T cells regulate memory-like CD8(+) T cell development
Several gene deficiency models promote the development of “innate CD8(+) T cells” that have diverse TCRs, but display a memory phenotype and rapidly produce cytokines. We here demonstrate that similar cells develop in Kruppel-Like Factor 2 (KLF2) deficient mice. However, this is not due to intrinsic...
Autores principales: | Weinreich, Michael A., Odumade, Oludare A., Jameson, Stephen C., Hogquist, Kristin A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051359/ https://www.ncbi.nlm.nih.gov/pubmed/20601952 http://dx.doi.org/10.1038/ni.1898 |
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