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HLA DNA Sequence Variation among Human Populations: Molecular Signatures of Demographic and Selective Events
Molecular differences between HLA alleles vary up to 57 nucleotides within the peptide binding coding region of human Major Histocompatibility Complex (MHC) genes, but it is still unclear whether this variation results from a stochastic process or from selective constraints related to functional dif...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051395/ https://www.ncbi.nlm.nih.gov/pubmed/21408106 http://dx.doi.org/10.1371/journal.pone.0014643 |