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HLA DNA Sequence Variation among Human Populations: Molecular Signatures of Demographic and Selective Events

Molecular differences between HLA alleles vary up to 57 nucleotides within the peptide binding coding region of human Major Histocompatibility Complex (MHC) genes, but it is still unclear whether this variation results from a stochastic process or from selective constraints related to functional dif...

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Detalles Bibliográficos
Autores principales: Buhler, Stéphane, Sanchez-Mazas, Alicia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051395/
https://www.ncbi.nlm.nih.gov/pubmed/21408106
http://dx.doi.org/10.1371/journal.pone.0014643