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Cdk-mediated phosphorylation of the Kvβ2 auxiliary subunit regulates Kv1 channel axonal targeting

Kv1 channels are concentrated at specific sites in the axonal membrane, where they regulate neuronal excitability. Establishing these distributions requires regulated dissociation of Kv1 channels from the neuronal trafficking machinery and their subsequent insertion into the axonal membrane. We find...

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Detalles Bibliográficos
Autores principales: Vacher, Hélène, Yang, Jae-Won, Cerda, Oscar, Autillo-Touati, Amapola, Dargent, Bénédicte, Trimmer, James S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051814/
https://www.ncbi.nlm.nih.gov/pubmed/21357749
http://dx.doi.org/10.1083/jcb.201007113