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OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation

Macroautophagy is a bulk degradation system conserved in all eukaryotic cells. A ubiquitin-like protein, Atg8, and its homologues are essential for autophagosome formation and act as a landmark for selective autophagy of aggregated proteins and damaged organelles. In this study, we report evidence d...

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Detalles Bibliográficos
Autores principales: Itoh, Takashi, Kanno, Eiko, Uemura, Takefumi, Waguri, Satoshi, Fukuda, Mitsunori
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051816/
https://www.ncbi.nlm.nih.gov/pubmed/21383079
http://dx.doi.org/10.1083/jcb.201008107