Cargando…

ATP-dependent and independent functions of Rad54 in genome maintenance

Rad54, a member of the SWI/SNF protein family of DNA-dependent ATPases, repairs DNA double-strand breaks (DSBs) through homologous recombination. Here we demonstrate that Rad54 is required for the timely accumulation of the homologous recombination proteins Rad51 and Brca2 at DSBs. Because replicati...

Descripción completa

Detalles Bibliográficos
Autores principales: Agarwal, Sheba, van Cappellen, Wiggert A., Guénolé, Aude, Eppink, Berina, Linsen, Sam E.V., Meijering, Erik, Houtsmuller, Adriaan, Kanaar, Roland, Essers, Jeroen
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051825/
https://www.ncbi.nlm.nih.gov/pubmed/21357745
http://dx.doi.org/10.1083/jcb.201011025