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H2A.Z nucleosomes enriched over active genes are homotypic

Nucleosomes that contain the histone variant H2A.Z are enriched around transcriptional start sites, but the mechanistic basis for enrichment is unknown. A single octameric nucleosome can contain two H2A.Z histones (homotypic) or one H2A.Z and one canonical H2A (heterotypic). To elucidate H2A.Z funct...

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Detalles Bibliográficos
Autores principales: Weber, Christopher M., Henikoff, Jorja G., Henikoff, Steven
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051840/
https://www.ncbi.nlm.nih.gov/pubmed/21057526
http://dx.doi.org/10.1038/nsmb.1926