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Notch signaling contributes to the maintenance of both normal neural stem cells and patient-derived glioma stem cells
BACKGROUND: Cancer stem cells (CSCs) play an important role in the development and recurrence of malignant tumors including glioma. Notch signaling, an evolutionarily conserved pathway mediating direct cell-cell interaction, has been shown to regulate neural stem cells (NSCs) and glioma stem cells (...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052197/ https://www.ncbi.nlm.nih.gov/pubmed/21342503 http://dx.doi.org/10.1186/1471-2407-11-82 |