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Notch signaling contributes to the maintenance of both normal neural stem cells and patient-derived glioma stem cells

BACKGROUND: Cancer stem cells (CSCs) play an important role in the development and recurrence of malignant tumors including glioma. Notch signaling, an evolutionarily conserved pathway mediating direct cell-cell interaction, has been shown to regulate neural stem cells (NSCs) and glioma stem cells (...

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Detalles Bibliográficos
Autores principales: Hu, Yi-Yang, Zheng, Min-Hua, Cheng, Gang, Li, Liang, Liang, Liang, Gao, Fang, Wei, Ya-Ning, Fu, Luo-An, Han, Hua
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052197/
https://www.ncbi.nlm.nih.gov/pubmed/21342503
http://dx.doi.org/10.1186/1471-2407-11-82