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The association between EGFR variant III, HPV, p16, c-MET, EGFR gene copy number and response to EGFR inhibitors in patients with recurrent or metastatic squamous cell carcinoma of the head and neck
BACKGROUND: We examine the potential prognostic and predictive roles of EGFR variant III mutation, EGFR gene copy number (GCN), human papillomavirus (HPV) infection, c-MET and p16(INK4A )protein expression in recurrent or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN). METHODS:...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052237/ https://www.ncbi.nlm.nih.gov/pubmed/21352589 http://dx.doi.org/10.1186/1758-3284-3-11 |