The association between EGFR variant III, HPV, p16, c-MET, EGFR gene copy number and response to EGFR inhibitors in patients with recurrent or metastatic squamous cell carcinoma of the head and neck

BACKGROUND: We examine the potential prognostic and predictive roles of EGFR variant III mutation, EGFR gene copy number (GCN), human papillomavirus (HPV) infection, c-MET and p16(INK4A )protein expression in recurrent or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN). METHODS:...

Descripción completa

Detalles Bibliográficos
Autores principales: Chau, Nicole G, Perez-Ordonez, Bayardo, Zhang, Katherine, Pham, Nhu-An, Ho, James, Zhang, Tong, Ludkovski, Olga, Wang, Lisa, Chen, Eric X, Tsao, Ming-Sound, Kamel-Reid, Suzanne, Siu, Lillian L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052237/
https://www.ncbi.nlm.nih.gov/pubmed/21352589
http://dx.doi.org/10.1186/1758-3284-3-11

Ejemplares similares

Ejemplares similares