Evc2 is a positive modulator of Hedgehog signalling that interacts with Evc at the cilia membrane and is also found in the nucleus

BACKGROUND: Evc is essential for Indian Hedgehog (Hh) signalling in the cartilage growth plate. The gene encoding Evc2 is in close proximity in divergent orientation to Evc and mutations in both human genes lead to the chondrodysplasia Ellis-van Creveld syndrome. RESULTS: Bioinformatic analysis reve...

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Detalles Bibliográficos
Autores principales: Blair, Helen J, Tompson, Stuart, Liu, Yu-Ning, Campbell, Jennifer, MacArthur, Katie, Ponting, Chris P, Ruiz-Perez, Victor L, Goodship, Judith A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052239/
https://www.ncbi.nlm.nih.gov/pubmed/21356043
http://dx.doi.org/10.1186/1741-7007-9-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052239/
https://www.ncbi.nlm.nih.gov/pubmed/21356043
http://dx.doi.org/10.1186/1741-7007-9-14

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