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Cell Cycle-Dependent Induction of Homologous Recombination by a Tightly Regulated I-SceI Fusion Protein

Double-strand break repair is executed by two major repair pathways: non-homologous end joining (NHEJ) and homologous recombination (HR). Whereas NHEJ contributes to the repair of ionizing radiation (IR)-induced double strand breaks (DSBs) throughout the cell cycle, HR acts predominantly during the...

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Detalles Bibliográficos
Autores principales: Hartlerode, Andrea, Odate, Shobu, Shim, Inbo, Brown, Jenifer, Scully, Ralph
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052302/
https://www.ncbi.nlm.nih.gov/pubmed/21408059
http://dx.doi.org/10.1371/journal.pone.0016501