Contribution of CgPDR1-Regulated Genes in Enhanced Virulence of Azole-Resistant Candida glabrata

In Candida glabrata, the transcription factor CgPdr1 is involved in resistance to azole antifungals via upregulation of ATP binding cassette (ABC)-transporter genes including at least CgCDR1, CgCDR2 and CgSNQ2. A high diversity of GOF (gain-of-function) mutations in CgPDR1 exists for the upregulatio...

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Detalles Bibliográficos
Autores principales: Ferrari, Sélène, Sanguinetti, Maurizio, Torelli, Riccardo, Posteraro, Brunella, Sanglard, Dominique
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052359/
https://www.ncbi.nlm.nih.gov/pubmed/21408004
http://dx.doi.org/10.1371/journal.pone.0017589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052359/
https://www.ncbi.nlm.nih.gov/pubmed/21408004
http://dx.doi.org/10.1371/journal.pone.0017589

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