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Geminin-Deficient Neural Stem Cells Exhibit Normal Cell Division and Normal Neurogenesis

Neural stem cells (NSCs) are the progenitors of neurons and glial cells during both embryonic development and adult life. The unstable regulatory protein Geminin (Gmnn) is thought to maintain neural stem cells in an undifferentiated state while they proliferate. Geminin inhibits neuronal differentia...

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Detalles Bibliográficos
Autores principales: Schultz, Kathryn M., Banisadr, Ghazal, Lastra, Ruben O., McGuire, Tammy, Kessler, John A., Miller, Richard J., McGarry, Thomas J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052383/
https://www.ncbi.nlm.nih.gov/pubmed/21408022
http://dx.doi.org/10.1371/journal.pone.0017736