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Subcellular Localization of Hexokinases I and II Directs the Metabolic Fate of Glucose

BACKGROUND: The first step in glucose metabolism is conversion of glucose to glucose 6-phosphate (G-6-P) by hexokinases (HKs), a family with 4 isoforms. The two most common isoforms, HKI and HKII, have overlapping tissue expression, but different subcellular distributions, with HKI associated mainly...

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Detalles Bibliográficos
Autores principales: John, Scott, Weiss, James N., Ribalet, Bernard
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052386/
https://www.ncbi.nlm.nih.gov/pubmed/21408025
http://dx.doi.org/10.1371/journal.pone.0017674