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The Ndc80 Loop Region Facilitates Formation of Kinetochore Attachment to the Dynamic Microtubule Plus End

Proper chromosome segregation in mitosis relies on correct kinetochore-microtubule (KT-MT) interactions. The KT initially interacts with the lateral surface of a single MT (lateral attachment) extending from a spindle pole and is subsequently anchored at the plus end of the MT (end-on attachment) [1...

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Detalles Bibliográficos
Autores principales: Maure, Jean-François, Komoto, Shinya, Oku, Yusuke, Mino, Akihisa, Pasqualato, Sebastiano, Natsume, Kayo, Clayton, Lesley, Musacchio, Andrea, Tanaka, Tomoyuki U.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052438/
https://www.ncbi.nlm.nih.gov/pubmed/21256019
http://dx.doi.org/10.1016/j.cub.2010.12.050