Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion

AIMS/HYPOTHESIS: We assessed whether per-arnt-sim (PAS) domain-containing protein kinase (PASK) is involved in the regulation of glucagon secretion. METHODS: mRNA levels were measured in islets by quantitative PCR and in pancreatic beta cells obtained by laser capture microdissection. Glucose tolera...

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Detalles Bibliográficos
Autores principales: da Silva Xavier, G., Farhan, H., Kim, H., Caxaria, S., Johnson, P., Hughes, S., Bugliani, M., Marselli, L., Marchetti, P., Birzele, F., Sun, G., Scharfmann, R., Rutter, J., Siniakowicz, K., Weir, G., Parker, H., Reimann, F., Gribble, F. M., Rutter, G. A.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052475/
https://www.ncbi.nlm.nih.gov/pubmed/21181396
http://dx.doi.org/10.1007/s00125-010-2010-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052475/
https://www.ncbi.nlm.nih.gov/pubmed/21181396
http://dx.doi.org/10.1007/s00125-010-2010-7

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